Does the NJ PATH card work in the NYC subway?

I am going to be relocating to upstate NJ and working in midtown. I will be looking to buy a 30-day unlimited use PATH train card in order to get into lower Manhattan, but I will probably have to take a subway from there to get to my office on 6th ave. Will I be able to use the PATH card to get around on the NYC subway, as well? Or do I need to purchase a separate transit card for the subway?